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Wenjie Zhu, Binghe Xu
《医学前沿(英文)》 2021年 第15卷 第2期 页码 208-220 doi: 10.1007/s11684-020-0795-4
关键词: endocrine-resistant HR+/HER2- advanced breast cancer randomized clinical trials meta-analysis targeted therapy
《医学前沿(英文)》 页码 907-923 doi: 10.1007/s11684-023-1009-7
RNA m<sup>6sup>A modification and its function in diseases
null
《医学前沿(英文)》 2018年 第12卷 第4期 页码 481-489 doi: 10.1007/s11684-018-0654-8
N6-methyladenosine (m6A) is the most common post-transcriptional RNA modification throughout the transcriptome, affecting fundamental aspects of RNA metabolism. m6A modification could be installed by m6A “writers” composed of core catalytic components (METTL3/METTL14/WTAP) and newly defined regulators and removed by m6A “erasers” (FTO and ALKBH5). The function of m6A is executed by m6A “readers” that bind to m6A directly (YTH domain-containing proteins, eIF3 and IGF2BPs) or indirectly (HNRNPA2B1). In the past few years, advances in m6A modulators (“writers,” “erasers,” and “readers”) have remarkably renewed our understanding of the function and regulation of m6A in different cells under normal or disease conditions. However, the mechanism and the regulatory network of m6A are still largely unknown. Moreover, investigations of the m6A physiological roles in human diseases are limited. In this review, we summarize the recent advances in m6A research and highlight the functional relevance and importance of m6A modification in in vitro cell lines, in physiological contexts, and in cancers.
动态二叉树表示环境的A<sup>*sup>算法及其在足球机器人路径规划中的实现
唐平,杨宜民
《中国工程科学》 2002年 第4卷 第9期 页码 50-53
提出采用二叉树表示二维空间的方法,对全局路径规划和局部路径规划进行综合考虑,设计移动机器人在复杂环境下对动态障碍物进行避障的A<sup>*sup>算法。
关键词: 动态二叉树 A<sup>*sup>算法 路径规划
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
《医学前沿(英文)》 2021年 第15卷 第4期 页码 608-620 doi: 10.1007/s11684-021-0836-7
关键词: t(8 21)(q22 q22) AML CD34+CD117dim/ CD34+CD117bri cell population gene expression prognosis
K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations
Pinfang LI,Biao ZHANG
《农业科学与工程前沿(英文)》 2014年 第1卷 第2期 页码 144-149 doi: 10.15302/J-FASE-2014016
关键词: Iris lactea Pall. var. chinensis (Fisch.) Koidz population K+ and Na+ ion flux non-invasive micro-test technique
Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU
《环境科学与工程前沿(英文)》 2015年 第9卷 第3期 页码 522-527 doi: 10.1007/s11783-014-0633-5
Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification
《环境科学与工程前沿(英文)》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1674-4
● Simultaneous NH4+/NO3– removal was achieved in the FeS denitrification system
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 1986-2000 doi: 10.1007/s11705-023-2337-5
关键词: sp3/sp2-hybridized C–N bond noble metal nanoparticle catalytic active site turnover frequency DFT
An electrochemical process that uses an Fe
Chaojie Jiang, Lifen Liu, John C. Crittenden
《环境科学与工程前沿(英文)》 2016年 第10卷 第4期 doi: 10.1007/s11783-016-0860-z
关键词: Bio-anode Photocatalytic cathode Fe0/TiO2 ESR Dye and antibiotics Advanced oxidation
NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway
《医学前沿(英文)》 2023年 第17卷 第2期 页码 263-274 doi: 10.1007/s11684-022-0935-0
关键词: melanoma neuropilin and tolloid-like 2 Ca2+/CaMKII signaling pathway
Advances of 12<sup>thsup> CAPS research symposium: young chemists and chemical engineers fronts
Guoping Hu, Baiqian Dai
《化学科学与工程前沿(英文)》 2021年 第15卷 第3期 页码 461-463 doi: 10.1007/s11705-020-2026-6
Advanced nitrogen and phosphorus removal in A
Jianhua WANG, Yongzhen PENG, Yongzhi CHEN
《环境科学与工程前沿(英文)》 2011年 第5卷 第3期 页码 474-480 doi: 10.1007/s11783-011-0360-0
关键词: Anoxic zone and biologic aerated filter (A2O-BAF) system domestic wastewater with low carbon-to-nitrogen ratio advanced nitrogen and phosphorus removal denitrifying phosphorus removal
陈景
《中国工程科学》 2004年 第6卷 第11期 页码 29-32
对氢分子离子提出了氢原子质子化的结构模型,从微观时标和宏观时标分析了H2<sup>+sup>中库仑吸引力和两核排斥力的动态平衡,认为氢原子畸变后的电子云在两核中点产生e/8的电荷重心时可以束缚住一个裸质子;据此推导出键长、键能及力常数的计算公式;使用原子单位分别获得Re=2 au,De=0.109 735 au,k=0.109
Symbiotic performance, shoot biomass and water-use efficiency of three groundnut (
Sofiya K. MUHABA, Felix D. DAKORA
《农业科学与工程前沿(英文)》 2020年 第7卷 第4期 页码 455-466 doi: 10.15302/J-FASE-2020354
Phosphorus is a key nutrient element involved in energy transfer for cellular metabolism, respiration and photosynthesis and its supply at low levels can affect legume nodulation, N fixation, and C assimilation. A two-year field study was conducted in Ethiopia in 2012 and 2013 to evaluate the effects of P supply on growth, symbiotic N nutrition, grain yield and water-use efficiency of three groundnut genotypes. Supplying P to the genotypes significantly increased their shoot biomass, symbiotic performance, grain yield, and C accumulation. There was, however, no effect on shoot δ C values in either year. Compared to the zero-P control, supplying 40 kg·ha P markedly increased shoot biomass by 77% and 66% in 2012 and 2013, respectively. In both years, groundnut grain yields were much higher at 20 and 30 kg·ha P. Phosphorus supply markedly reduced shoot δ N values and increased the %Ndfa and amount of N-fixed, indicating the direct involvement of P in promoting N fixation in nodulated groundnut. The three genotypes differed significantly in δ N, %Ndfa, N-fixed, grain yield, C concentration, and δ C. The phosphorus × genotype interaction was also significant for shoot DM, N content, N-fixed and soil N uptake.
关键词: shoot yield N-fixed %Ndfa δ15N δ13C water-use efficiency
标题 作者 时间 类型 操作
resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor receptor 2-negative (HR
Wenjie Zhu, Binghe Xu
期刊论文
frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast
期刊论文
Clinical significance of CD34<sup>+sup>CD117<sup>dimsup>/CD34<sup>+sup>CD117<sup>brisup> myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
期刊论文
K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations
Pinfang LI,Biao ZHANG
期刊论文
Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites
期刊论文
Advances of 12<sup>thsup> CAPS research symposium: young chemists and chemical engineers fronts
Guoping Hu, Baiqian Dai
期刊论文